Selecting β-thalassemia Patients for Gene Therapy: A Decision-making Algorithm

Gene Therapy for β - Thalassemia

Gene transfer for β-thalassemia requires gene transfer into hematopoietic stem cells using integrating vectors that direct regulated expression of β globin at therapeutic levels. Among integrating vectors, oncoretroviral vectors carrying the human βglobin gene and portions of the locus control region (LCR) have suffered from problems of vector instability, low titers and variable expression. In...

AAV Mediated β-Thalassemia Gene Therapy

designing a decision making model for selecting technology transfer projects

in this paper, first, a conceptual framework has been developed and while truly recognizing different aspects of the technology transfer process, it is trying to introduce a decision-making methodology in the choice of projects. then by choosing effective variables in technology transfer process, a multiple criteria decision-making (mcdm) model has been designed, so that the choice of appropria...

A New Hybrid Decision Making Method for Selecting Roller Concrete Road Pavement Technology Transfer Method

In today's competitive market, technology transfer is an important problem for firms, organizations and governments. Therefore, making right decisions on selecting a suitable technology and designing an appropriate process to transfer it may have significant influence on the performance of organizations. In this paper, we present a new method to obtain a suitable technology transfer strategy fo...

Selecting a provider: what factors influence patients' decision making?

Each year consumers make a variety of decisions relating to their healthcare. Some experts argue that stronger consumer engagement in decisions about where to obtain medical care is an important mechanism for improving efficiency in healthcare delivery and financing. Consumers' ability and motivation to become more active decision makers are affected by several factors, including financial ince...